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Gene Discovery Could Lead to a New Approach in Preventive and Restorative Dentistry

February 24th, 2009 · No Comments

dental research


The strongest substance in the human body might be duplicable as a result of scientists finding the gene responsible for producing tooth enamel. Ctip2, a transcription factor, has been known to contribute to immune response, as well as development of skin and the nervous system. This gene is now known to be responsible for tooth enamel. Scientists hope that the finding will advance cavity prevention, restoration of decayed teeth, and possibly the creation of replacement teeth.

Stem cell research to this point has allowed labs to grow the inner part of teeth, but they could not produce enamel to coat teeth. Now that we know Ctip2 produces enamel, research could progress significantly and quickly.

Researchers at multiple colleges at Oregon State University and Genetique et de Biologie Moleculaire et Cellulaire in France are responsible for the finding. An article will be published in Proceedings of the National Academy of Sciences with a full report.

SOURCE: MedicalNewsToday

Tags: Clinical

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