Dentists, oral surgeons, periodontists, and medical surgeons use oral tissue grafts for a number of procedures. Biocompatibility of the grafts is an important factor for successful transplantation. Using skin for an oral tissue graft poses problems such as bulkiness, hair growth, and sweating. To this point, human engineered oral tissue grafts have not been availalble. But not any more.
Recent Swedish research shows that a new, engineered oral tissue substitute is proving effective in clinical applications. The engineered tissue is created from a small analogous oral tissue graft that is expanded in the lab over three weeks. The new graft is biocompatible because of the source, and it has characteristics of natural oral tissue, rather than skin.
To this point, oral tissue graft engineering research has lagged behind that of skin. This exciting development, with research directed by lead author Dr. Susan Gibbs at the VU University Medical Centre in Amsterdam, is a breakthrough for oral surgery.
SOURCE: Science Daily
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