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What is HCI? – A Word Definition From the Webopedia Computer Dictionary

Short for human-computer Interaction, a discipline concerned with the study, design, construction and implementation of human-centric interactive computer systems. A user interface, such as a GUI, is how a human interacts with a computer, and HCI goes beyond designing screens and menus that are easier to use and studies the reasoning behind building specific functionality into computers and the long-term effects that systems will have on humans.
HCI is a very broad discipline that encompasses different specialties with different concerns regarding computer development: computer science is concerned with the application design and engineering of the human interfaces; sociology and anthropology are concerned with the interactions between technology, work and organization and the way that human systems and technical systems mutually adapt to each other; ergonomics is concerned with the safety of computer systems and the safe limits of human cognition and sensation; psychology is concerned with the cognitive processes of humans and the behavior of users; linguistics is concerned with the development of human and machine languages and the relationship between the two.